Article
Replication study of SNP associations for colorectal cancer in Hong Kong Chinese.
British journal of cancer - 18 Jan 2011
Ho J W, Choi S-c, Lee Y-f, Hui T C, Cherny S S, Garcia-Barceló M-M, Carvajal-Carmona L, Liu R, To S-h, Yau T-k, Chung C C, Yau C C, Hui S M, Lau P Y, Yuen C-h, Wong Y-w, Ho S, Fung S S, Tomlinson I P, Houlston R S, Cheng K K, Sham P C
Abstract excerpt
BACKGROUND: Recent genome-wide association studies of colorectal cancer (CRC) have identified common single-nucleotide polymorphisms (SNPs) mapping to 10 independent loci that confer modest increased risk. These studies have been conducted in European populations and it is unclear whether these observations generalise to populations with different ethnicities and rates of CRC. METHODS: An association study was...
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