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Article

Molecular Genetics of Lung Cancer

13 Jan 2003

Abstract excerpt

Lung cancer results from multiple changes in the genome of susceptible pulmonary cells caused by exposure to carcinogens found in tobacco smoke, the environment, or the workplace. Recent studies suggest that histologically apparent lung cancer is due to the sequential accumulation of specific genetic and morphologic changes to the normal epithelial cells of the lung. Positive signallers, such as those mediated by...

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PMID: 12471176
DOI: 10.1146/annurev.med.54.101601.152202

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