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Metabolomic Signatures in Guinea Pigs Infected with Epidemic-Associated W-Beijing Strains of <i>Mycobacterium tuberculosis</i>

8 Aug 2012

Abstract excerpt

With the understanding that the laboratory propagated strain of Mycobacterium tuberculosis H37Rv is of modest virulence and is drug susceptible, in the present study, we performed a nuclear magnetic resonance-based metabolomic analysis of lung tissues and serum obtained from guinea pigs infected by low dose aerosol exposure to clinical isolates of Mycobacterium tuberculosis. High Resolution Magic Angle Spinning...

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PMID: 22873951
DOI: 10.1021/pr300345x

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