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The W-Beijing Lineage of <i>Mycobacterium tuberculosis</i> Overproduces Triglycerides and Has the DosR Dormancy Regulon Constitutively Upregulated

20 Jan 2007

Abstract excerpt

The Beijing family of Mycobacterium tuberculosis strains has been associated with epidemic spread and an increased likelihood of developing drug resistance. The characteristics that predispose this family to such clinical outcomes have not been identified, although one potential candidate, the phenolic glycolipid PGL-tb, has been shown to mediate a fulminant lethal disease in mice and rabbits due to...

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PMID: 17237171
DOI: 10.1128/jb.01670-06

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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