Article
DLA class II alleles and haplotypes are associated with risk for and protection from chronic hepatitis in the English Springer spaniel.
PloS one - 1 Jan 2012
Bexfield Nicholas H, Watson Penny J, Aguirre-Hernandez Jesús, Sargan David R, Tiley Laurence, Heeney Jonathan L, Kennedy Lorna J
Abstract excerpt
Chronic hepatitis (CH) is common in dogs in the United Kingdom. An increased prevalence of the disease is seen in the English Springer spaniel (ESS), and this breed suffer from a severe form with young to middle aged female dogs being predisposed. The disease shares histological features with those of human viral hepatitis, although the specific aetiological agent has not yet been identified. The aim of the...
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