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Article

Association of Doberman hepatitis to canine major histocompatibility complex II.

Tissue antigens - 1 Jan 2011

Dyggve H, Kennedy L J, Meri S, Spillmann T, Lohi H, Speeti M

Abstract excerpt

Doberman hepatitis (DH) is a chronic and progressive inflammatory liver disease that mainly affects female dogs. The high incidence of chronic hepatitis in Dobermans is suggestive of a genetic predisposition. DH is characterized by mononuclear cell infiltration and copper accumulation in the liver and major histocompatibility complex (MHC) class II antigen expression in the hepatocytes. In dogs, the MHC is...

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PMID: 20946186
DOI: 10.1111/j.1399-0039.2010.01575.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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