Article
Dog leukocyte antigen genotyping across class I and class II genes in beagle dogs as laboratory animals.
Immunogenetics - 1 Aug 2024
Konno Hiroya, Miyamae Jiro, Kataoka Hiroko, Akai Makoto, Miida Hiroaki, Tsuchiya Yoshimi
Abstract excerpt
Dog leukocyte antigen (DLA) polymorphisms have been found to be associated with inter-individual variations in the risk, susceptibility, and severity of immune-related phenomena. While DLA class II genes have been extensively studied, less research has been performed on the polymorphisms of DLA class I genes, especially in beagle dogs commonly used as laboratory animals for safety evaluations in drug development....
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