Article
Single nucleotide polymorphisms in major histocompatibility class II haplotypes are associated with potential resistance to inflammatory bowel disease in German shepherd dogs.
Veterinary immunology and immunopathology - 1 Dec 2016
Peiravan Atiyeh, Allenspach Karin, Boag Alisdair M, Soutter Francesca, Holder Angela, Catchpole Brian, Kennedy Lorna J, Werling Dirk, Procoli Fabio
Abstract excerpt
German shepherd dogs (GSD) in the UK are at increased risk of developing the Inflammatory Bowel Disaese (IBD). IBD is believed to be a multifactorial immune mediated disease affecting genetically predisposed dogs. The aim of the current study was to investigate whether susceptibility to IBD in GSD is associated with the major histocompatibility complex (MHC) class II locus (Dog Leukocyte Antigen, DLA)....
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