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Article

Increased genetic risk or protection for canine autoimmune lymphocytic thyroiditis in Giant Schnauzers depends on DLA class II genotype.

Tissue antigens - 1 Jun 2010

Wilbe M, Sundberg K, Hansen I R, Strandberg E, Nachreiner R F, Hedhammar A, Kennedy L J, Andersson G, Björnerfeldt S

Abstract excerpt

Dogs represent an excellent comparative model for autoimmune thyroiditis as several dog breeds develop canine lymphocytic thyroiditis (CLT), which is clinically similar to Hashimoto's thyroiditis in human. We obtained evidence that dog leukocyte antigen (DLA) class II genotype function as either genetic risk factor that predisposes for CLT or as protective factor against the disease. Genetic diversity at their...

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PMID: 20210920
DOI: 10.1111/j.1399-0039.2010.01449.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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