Article
Identification of susceptibility and protective major histocompatibility complex haplotypes in canine diabetes mellitus.
Tissue antigens - 1 Dec 2006
Kennedy L J, Davison L J, Barnes A, Short A D, Fretwell N, Jones C A, Lee A C, Ollier W E R, Catchpole B
Abstract excerpt
Diabetes mellitus occurs spontaneously in dogs, which is believed to have an autoimmune component and to be a model of human latent autoimmune diabetes of adults (LADA). Some dog breeds (e.g. Samoyed) are particularly predisposed, whereas others (e.g. Boxer) are highly resistant. With the completion of the Dog Genome Assembly, comparative genomic studies of complex diseases in dogs, including diabetes, could...
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