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Article

MHC class II association study in eight breeds of dog with hypoadrenocorticism.

Immunogenetics - 1 Apr 2013

Massey Jonathan, Boag Alisdair, Short Andrea D, Scholey Rachel A, Henthorn Paula S, Littman Meryl P, Husebye Eystein, Catchpole Brian, Pedersen Niels, Mellersh Cathryn S, Ollier William E R, Kennedy Lorna J

Abstract excerpt

Canine hypoadrenocorticism is an endocrine disorder characterised by inadequate secretion of steroid hormones from the adrenal glands. Pathology results from immune-mediated destruction of the adrenal cortex, which is similar to that seen in the human Addison's disease. Both the canine and human diseases have similar clinical presentation, with the diagnosis based on performing a dynamic adrenocorticotropic...

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PMID: 23358933
DOI: 10.1007/s00251-013-0680-2

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