Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Risk of anal furunculosis in German shepherd dogs is associated with the major histocompatibility complex.

Tissue antigens - 1 Jan 2008

Kennedy L J, O'Neill T, House A, Barnes A, Kyöstilä K, Innes J, Fretwell N, Day M J, Catchpole B, Lohi H, Ollier W E R

Abstract excerpt

Anal furunculosis (AF) is a chronic, progressive inflammatory disease of the perianal tissues most frequently affecting middle-aged or older German Shepherd dogs (GSD). Because this breed accounts for over 80% of all reported cases, there is likely to be a genetic association with disease susceptibility. Although there are some similarities with perianal fistulation that occurs in human Crohn's disease, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Anus Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dog Diseases

Share to Genetic Predisposition to Disease

Share to Major Histocompatibility Complex

Share to Milk Quality and Mastitis in Dairy Cows

Share to Risk Factors

Source

Identifiers

PMID: 17999655
DOI: 10.1111/j.1399-0039.2007.00964.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Risk of anal furunculosis in German shepherd dogs is associated with the major histocompatibility complex.PMID 17999655Read ↗

Association of canine anal furunculosis with TNFA is secondary to linkage disequilibrium with DLA-DRB1*.Semantic proximity Read ↗

Genetics of canine anal furunculosis in the German shepherd dog.Semantic proximity Read ↗

Single nucleotide polymorphisms in major histocompatibility class II haplotypes are associated with potential resistance to inflammatory bowel disease in German shepherd dogs.Semantic proximity Read ↗

Dog leukocyte antigen (DLA) class II genotypes associated with chronic enteropathy in French bulldogs and miniature dachshunds.Semantic proximity Read ↗

MHC class II is an important genetic risk factor for canine systemic lupus erythematosus (SLE)-related disease: implications for reproductive success.Semantic proximity Read ↗

DLA class II alleles and haplotypes are associated with risk for and protection from chronic hepatitis in the English Springer spaniel.Semantic proximity Read ↗

Dog leukocyte antigen genotyping across class I and class II genes in beagle dogs as laboratory animals.Semantic proximity Read ↗

Genome-wide association studies of inflammatory bowel disease in German shepherd dogs.Semantic proximity Read ↗

Expanded dog leukocyte antigen (DLA) single nucleotide polymorphism (SNP) genotyping reveals spurious class II associations.Semantic proximity Read ↗

Association of Doberman hepatitis to canine major histocompatibility complex II.Semantic proximity Read ↗

Polymorphisms in the TLR4 and TLR5 gene are significantly associated with inflammatory bowel disease in German shepherd dogs.Semantic proximity Read ↗

Multiple autoimmune diseases syndrome in Italian Greyhounds: preliminary studies of genome-wide diversity and possible associations within the dog leukocyte antigen (DLA) complex.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.