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Article

Study of KRAS new predictive marker in a clinical laboratory.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Dec 2012

Bando Inmaculada, Cillero Lourdes, Sanz-Ortega Julián, Llovet Patricia, Pescador Paula, Ferrer Milagros, de la Hoya Miguel, Sastre Javier, García Eduardo Díaz-Rubio, Caldés Trinidad

Abstract excerpt

BACKGROUND: The presence of somatic mutations in the KRAS gene has been identified as a reliable strong negative predictor for the response to targeting the epidermal growth factor receptor (EGFR), in patients with metastatic colorectal cancer and the use of anti-EGFR monoclonal antibodies such a...

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Source

Identifiers

PMID: 22865324
DOI: 10.1007/s12094-012-0886-z

Genes

KRAS
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22865324-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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