Article
KRAS assay selection: sensitivity and accuracy in clinical application.
Molecular biology reports - 1 Mar 2012
Herreros-Villanueva Marta, Aggarwal Gaurav
Abstract excerpt
KRAS mutation status is routinely tested before the administration of chemotherapeutic agents that target EGFR such as cetuximab and panitumumab. Various commercial assays to analyze KRAS mutational status are currently certified for in vitro diagnostic use. However, the differences in the operational characteristics of the different assays have not been investigated. Since different assays could be different in...
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