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The role of Transcription Factor IIH complex in nucleotide excision repair

7 Aug 2023

Abstract excerpt

DNA damage occurs throughout life from a variety of sources, and it is imperative to repair damage in a timely manner to maintain genome stability. Thus, DNA repair mechanisms are a fundamental part of life. Nucleotide excision repair (NER) plays an important role in the removal of bulky DNA adducts, such as cyclobutane pyrimidine dimers from ultraviolet light or DNA crosslinking damage from platinum-based...

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PMID: 37545038
DOI: 10.1002/em.22568

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