Article
The Escherichia coli GTPase ObgE modulates hydroxyl radical levels in response to DNA replication fork arrest.
The FEBS journal - 1 Oct 2012
Kint Cyrielle I, Verstraeten Natalie, Wens Inez, Liebens Veerle R, Hofkens Johan, Versées Wim, Fauvart Maarten, Michiels Jan
Abstract excerpt
Obg proteins are universally conserved GTP-binding proteins that are essential for viability in bacteria. Homologs in different organisms are involved in various cellular processes, including DNA replication. The goal of this study was to analyse the structure-function relationship of Escherichia coli ObgE with regard to DNA replication in general and sensitivity to stalled replication forks in particular....
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