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Article

Stimulation of Wnt/ß-catenin pathway in human CD8+ T lymphocytes from blood and lung tumors leads to a shared young/memory phenotype.

PloS one - 1 Jan 2012

Forget Marie-Andrée, Huon Yannick, Reuben Alexandre, Grange Cécile, Liberman Moïshe, Martin Jocelyne, Mes-Masson Anne-Marie, Arbour Nathalie, Lapointe Réjean

Abstract excerpt

Cancer can be treated by adoptive cell transfer (ACT) of T lymphocytes. However, how to optimally raise human T cells to a differentiation state allowing the best persistence in ACT is a challenge. It is possible to differentiate mouse CD8(+) T cells towards stem cell-like memory (T(SCM)) phenoty...

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Source

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Identifiers

PMID: 22859966
DOI: 10.1371/journal.pone.0041074
PMCID: PMC3408435

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22859966-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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