Article
To Remember or to Forget: The Role of Good and Bad Memories in Adoptive T Cell Therapy for Tumors.
Frontiers in immunology - 1 Jan 2020
Mondino Anna, Manzo Teresa
Abstract excerpt
The generation of immunological memory is a hallmark of adaptive immunity by which the immune system "remembers" a previous encounter with an antigen expressed by pathogens, tumors, or normal tissues; and, upon secondary encounters, mounts faster and more effective recall responses. The establishment of T cell memory is influenced by both cell-intrinsic and cell-extrinsic factors, including genetic, epigenetic...
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