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Article

Mutant GNAS detected in duodenal collections of secretin-stimulated pancreatic juice indicates the presence or emergence of pancreatic cysts.

Gut - 1 Jul 2013

Kanda Mitsuro, Knight Spencer, Topazian Mark, Syngal Sapna, Farrell James, Lee Jeffrey, Kamel Ihab, Lennon Anne Marie, Borges Michael, Young Angela, Fujiwara Sho, Seike Junro, Eshleman James, Hruban Ralph H, Canto Marcia Irene, Goggins Michael

Abstract excerpt

OBJECTIVE: Pancreatic cysts are commonly detected in patients undergoing pancreatic imaging. Better approaches are needed to characterise these lesions. In this study we evaluated the utility of detecting mutant DNA in secretin-stimulated pancreatic juice. DESIGN: Secretin-stimulated pancreatic juice was collected from the duodenum of 291 subjects enrolled in Cancer of the Pancreas Screening trials at five US...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

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Share to GTP-Binding Protein alpha Subunits, Gs

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Source

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Identifiers

PMID: 22859495
DOI: 10.1136/gutjnl-2012-302823
PMCID: PMC3893110

Genes

GNAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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