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Article

Clinical utility of incorporating next-generation sequencing results in the management algorithm of pancreatic cysts.

Gastrointestinal endoscopy - 1 Aug 2025

Jones Alex R, Bardhi Olgert, Polanco Patricio, Ellis Daniel, Bishop Christofer, Coleman Veronica, Foley Blake, Khatri Gaurav, Goldschmiedt Markus, Mansour John, Vanderveldt Hendrikus, Singhi Aatur, Kubiliun Nisa, Sawas Tarek

Abstract excerpt

BACKGROUND AND AIMS: Pancreatic cysts often pose challenges in predicting malignant progression. Next-generation sequencing (NGS) has become an appealing ancillary diagnostic test. The diagnostic performance is well characterized, but the impact on clinical management remains unclear. We evaluated the efficacy of integrating NGS into cyst management algorithms. METHODS: This single-center retrospective study...

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PMID: 39818341
DOI: 10.1016/j.gie.2025.01.005

Genes

GNAS
KRAS
VHL

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