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Article

TMEM106B risk variant is implicated in the pathologic presentation of Alzheimer disease.

Neurology - 14 Aug 2012

Rutherford Nicola J, Carrasquillo Minerva M, Li Ma, Bisceglio Gina, Menke Joshua, Josephs Keith A, Parisi Joseph E, Petersen Ronald C, Graff-Radford Neill R, Younkin Steven G, Dickson Dennis W, Rademakers Rosa

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Identifiers

PMID: 22855871
DOI: 10.1212/WNL.0b013e318264e3ac
PMCID: PMC3467659

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Related research

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TMEM106B risk variant is implicated in the pathologic presentation of Alzheimer disease.PMID 22855871Read ↗

TMEM106B is a susceptibility locus for Ftld.Semantic proximity Read ↗

What we know about TMEM106B in neurodegeneration.Semantic proximity Read ↗

C-terminal TMEM106B fragments in human brain correlate with disease-associated TMEM106B haplotypesSemantic proximity Read ↗

TMEM106B coding variant is protective and deletion detrimental in a mouse model of tauopathy.Semantic proximity Read ↗

rs1990622 variant associates with Alzheimer's disease and regulates TMEM106B expression in human brain tissues.Semantic proximity Read ↗

TMEM106B and APOE polymorphisms interact to confer risk for late-onset Alzheimer's disease in Han Chinese.Semantic proximity Read ↗

TMEM106B coding variant is protective and deletion detrimental in a mouse model of tauopathySemantic proximity Read ↗

Case report: TMEM106B haplotype alters penetrance of GRN mutation in frontotemporal dementia familySemantic proximity Read ↗

TMEM106B a novel risk factor for frontotemporal lobar degeneration.Semantic proximity Read ↗

A common Alu element insertion in the 3’UTR of <i>TMEM106B</i> is associated with an increased risk of dementiaSemantic proximity Read ↗

TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia.Semantic proximity Read ↗

A common Alu insertion in the 3'UTR of TMEM106B is associated with risk of dementia.Semantic proximity Read ↗

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