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Article

Spatial and functional relationships among Pol V-associated loci, Pol IV-dependent siRNAs, and cytosine methylation in the Arabidopsis epigenome.

Genes & development - 15 Aug 2012

Wierzbicki Andrzej T, Cocklin Ross, Mayampurath Anoop, Lister Ryan, Rowley M Jordan, Gregory Brian D, Ecker Joseph R, Tang Haixu, Pikaard Craig S

Abstract excerpt

Multisubunit RNA polymerases IV and V (Pols IV and V) mediate RNA-directed DNA methylation and transcriptional silencing of retrotransposons and heterochromatic repeats in plants. We identified genomic sites of Pol V occupancy in parallel with siRNA deep sequencing and methylcytosine mapping, comparing wild-type plants with mutants defective for Pol IV, Pol V, or both Pols IV and V. Approximately 60% of Pol...

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Identifiers

PMID: 22855789
DOI: 10.1101/gad.197772.112
PMCID: PMC3426761

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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