Article
Highly integrated single-base resolution maps of the epigenome in Arabidopsis.
Cell - 2 May 2008
Lister Ryan, O'Malley Ronan C, Tonti-Filippini Julian, Gregory Brian D, Berry Charles C, Millar A Harvey, Ecker Joseph R
Abstract excerpt
Deciphering the multiple layers of epigenetic regulation that control transcription is critical to understanding how plants develop and respond to their environment. Using sequencing-by-synthesis technology we directly sequenced the cytosine methylome (methylC-seq), transcriptome (mRNA-seq), and small RNA transcriptome (smRNA-seq) to generate highly integrated epigenome maps for wild-type Arabidopsis thaliana and...
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