Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Increased susceptibility to Salmonella infection in signal regulatory protein α-deficient mice.

Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 2012

Li Lin-Xi, Atif Shaikh M, Schmiel Shirdi E, Lee Seung-Joo, McSorley Stephen J

Abstract excerpt

Recent studies have shed light on the connection between elevated erythropoetin production/spleen erythropoiesis and increased susceptibility to Salmonella infection. In this article, we provide another mouse model, the SIRPα-deficient (Sirpα⁻/⁻) mouse, that manifests increased erythropoiesis as well as heightened susceptibility to Salmonella infection. Sirpα⁻/⁻ mice succumbed to systemic infection with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chlamydia Infections
Share to Mice, 129 Strain

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Congenic

Share to Mice, Transgenic

Share to Receptors, Immunologic

Share to Salmonella Infections

Share to Salmonella typhimurium

Share to Up-Regulation

Source

Open in PubMed Open full text

Identifiers

PMID: 22851710
DOI: 10.4049/jimmunol.1200429
PMCID: PMC3424330

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased susceptibility to Salmonella infection in signal regulatory protein α-deficient mice.PMID 22851710Read ↗

Requirement of SIRPα for protective immunity against Leishmania major.Semantic proximity Read ↗

Non-Hematopoietic and Hematopoietic SIRPα Signaling Differently Regulates Murine B Cell Maturation in Bone Marrow and Spleen.Semantic proximity Read ↗

Regulation by SIRPα of dendritic cell homeostasis in lymphoid tissues.Semantic proximity Read ↗

Exacerbated experimental colitis in TNFAIP8-deficient mice.Semantic proximity Read ↗

PIR-B-deficient mice are susceptible to Salmonella infection.Semantic proximity Read ↗

Roles of Salmonella enterica serovar Typhimurium encoded Peptidase N during systemic infection of Ifnγ-/- mice.Semantic proximity Read ↗

Incremental expression of Tlr4 correlates with mouse resistance to Salmonella infection and fine regulation of relevant immune genes.Semantic proximity Read ↗

SIRPα controls the activity of the phagocyte NADPH oxidase by restricting the expression of gp91(phox).Semantic proximity Read ↗

Effect of the mouse Nramp1 genotype on the expression of IFN-gamma gene in early response to Salmonella infection.Semantic proximity Read ↗

Critical role of CD28 in protective immunity against Salmonella typhimurium.Semantic proximity Read ↗

Lineage extrinsic and intrinsic control of immunoregulatory cell numbers by SHIPSemantic proximity Read ↗

The spleen dictates platelet destruction, anti-platelet antibody production, and lymphocyte distribution patterns in a murine model of immune thrombocytopenia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.