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Article

PIR-B-deficient mice are susceptible to Salmonella infection.

Journal of immunology (Baltimore, Md. : 1950) - 15 Sept 2008

Torii Ikuko, Oka Satoshi, Hotomi Muneki, Benjamin William H, Takai Toshiyuki, Kearney John F, Briles David E, Kubagawa Hiromi

Abstract excerpt

Paired Ig-like receptors of activating (PIR-A) and inhibitory (PIR-B) isoforms are expressed by many hematopoietic cells, including B lymphocytes and myeloid cells. To determine the functional roles of PIR-A and PIR-B in primary bacterial infection, PIR-B-deficient (PIR-B(-/-)) and wild-type (WT) control mice were injected i.v. with an attenuated strain of Salmonella enterica Typhimurium (WB335). PIR-B(-/-) mice...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18768880
DOI: 10.4049/jimmunol.181.6.4229
PMCID: PMC2613810

Genes

PIR
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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