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Article

SVM-based generalized multifactor dimensionality reduction approaches for detecting gene-gene interactions in family studies.

Genetic epidemiology - 1 Feb 2012

Fang Yao-Hwei, Chiu Yen-Feng

Abstract excerpt

Gene-gene interaction plays an important role in the etiology of complex diseases, which may exist without a genetic main effect. Most current statistical approaches, however, focus on assessing an interaction effect in the presence of the gene's main effects. It would be very helpful to develop methods that can detect not only the gene's main effects but also gene-gene interaction effects regardless of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22851472
DOI: 10.1002/gepi.21602

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