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Article

Utilizing Saccharomyces cerevisiae to identify aneuploidy and cancer susceptibility genes.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010

Strome Erin D, Plon Sharon E

Abstract excerpt

Cancers are commonly characterized as having an abnormal number of chromosomes, termed aneuploidy, which arise due to genomic instability. There is still debate over whether aneuploidy is a driving force of the disease or a resulting phenotype; however, the presence of aneuploidy can be used to grade the malignant potential of certain types of cancer. A simple hypothesis is that genome instability itself is...

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PMID: 20721738
DOI: 10.1007/978-1-60761-759-4_5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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