Article
Estimating the number of one-step beneficial mutations.
Statistical applications in genetics and molecular biology - 19 Jul 2012
Wojtowicz Andrzej J, Miller Craig R, Joyce Paul
Abstract excerpt
Mutations that confer a selective advantage to an organism are the raw material upon which natural selection acts. The number of such mutations that are available is a central quantity of interest for understanding the tempo and trajectory of adaptive evolution. While this quantity is typically unknown, it can be estimated with varying levels of accuracy based on data obtained experimentally. We propose a method...
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