Article
The last rRNA methyltransferase of E. coli revealed: the yhiR gene encodes adenine-N6 methyltransferase specific for modification of A2030 of 23S ribosomal RNA.
RNA (New York, N.Y.) - 1 Sept 2012
Golovina Anna Y, Dzama Margarita M, Osterman Ilya A, Sergiev Petr V, Serebryakova Marina V, Bogdanov Alexey A, Dontsova Olga A
Abstract excerpt
The ribosomal RNA (rRNA) of Escherichia coli contains 24 methylated residues. A set of 22 methyltransferases responsible for modification of 23 residues has been described previously. Herein we report the identification of the yhiR gene as encoding the enzyme that modifies the 23S rRNA nucleotide A2030, the last methylated rRNA nucleotide whose modification enzyme was not known. YhiR prefers protein-free 23S rRNA...
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