Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of a BMP9 haplotype with ossification of the posterior longitudinal ligament (OPLL) in a Chinese population.

PloS one - 1 Jan 2012

Ren Yuan, Liu Zhi-zhong, Feng Jie, Wan Hong, Li Jun-hua, Wang Hao, Lin Xin

Abstract excerpt

Direct or ex vivo BMP9 adenoviral gene therapy can induce massive bone formation at the injection sites and clearly promote spinal fusion. A comprehensive analysis of the osteogenic activity indicated that BMP9 was one of the most potent inducers of osteogenic differentiation both in vitro and in vivo among 14 types of human BMPs. However, genetic variations and whether they correlated with OPLL were not...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Haplotypes

Share to Linkage Disequilibrium

Share to Polymorphism, Single Nucleotide

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 22829878
DOI: 10.1371/journal.pone.0040587
PMCID: PMC3400650

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of a BMP9 haplotype with ossification of the posterior longitudinal ligament (OPLL) in a Chinese population.PMID 22829878Read ↗

A new haplotype in BMP4 implicated in ossification of the posterior longitudinal ligament (OPLL) in a Chinese population.Semantic proximity Read ↗

Linkage of three polymorphisms on chromosome 20p12 to ossification of the posterior longitudinal ligament of spine and its severity in Han Chinese patients.Semantic proximity Read ↗

Role of Runx2 polymorphisms in risk and prognosis of ossification of posterior longitudinal ligament.Semantic proximity Read ↗

Ossification of the Posterior Longitudinal Ligament: An Update on Its Biology, Epidemiology, and Natural HistorySemantic proximity Read ↗

T allele at site 6007 of bone morphogenetic protein-4 gene increases genetic susceptibility to ossification of the posterior longitudinal ligament in male Chinese Han population.Semantic proximity Read ↗

A single nucleotide polymorphism in the human bone morphogenetic protein-2 gene (109T > G) affects the Smad signaling pathway and the predisposition to ossification of the posterior longitudinal ligament of the spine.Semantic proximity Read ↗

[Genomic analysis of ossification of the posterior longitudinal ligament].Semantic proximity Read ↗

Targeted next-generation sequencing reveals multiple deleterious variants in OPLL-associated genes.Semantic proximity Read ↗

Genetic insights into ossification of the posterior longitudinal ligament of the spineSemantic proximity Read ↗

The Pathogenesis of Ossification of the Posterior Longitudinal LigamentSemantic proximity Read ↗

RUNX2 polymorphisms associated with OPLL and OLF in the Han population.Semantic proximity Read ↗

The COL6A1 rs201153092 single nucleotide polymorphism, associates with thoracic ossification of the posterior longitudinal ligament.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.