Article
A tale of three next generation sequencing platforms: comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers.
BMC genomics - 24 Jul 2012
Quail Michael A, Smith Miriam, Coupland Paul, Otto Thomas D, Harris Simon R, Connor Thomas R, Bertoni Anna, Swerdlow Harold P, Gu Yong
Abstract excerpt
BACKGROUND: Next generation sequencing (NGS) technology has revolutionized genomic and genetic research. The pace of change in this area is rapid with three major new sequencing platforms having been released in 2011: Ion Torrent's PGM, Pacific Biosciences' RS and the Illumina MiSeq. Here we compare the results obtained with those platforms to the performance of the Illumina HiSeq, the current market leader. In...
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