Generalizable characteristics of false-positive bacterial variant calls.

Abstract excerpt

Minimizing false positives is a critical issue when variant calling as no method is without error. It is common practice to post-process a variant-call file (VCF) using hard filter criteria intended to discriminate true-positive (TP) from false-positive (FP) calls. These are applied on the simple principle that certain characteristics are disproportionately represented among the set of FP calls and that a...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bacteria
• Share to Bacteriological Techniques
• Share to Computational Biology