Article
The plasma concentration of HDL-associated apoM is influenced by LDL receptor-mediated clearance of apoB-containing particles.
Journal of lipid research - 1 Oct 2012
Christoffersen Christina, Benn Marianne, Christensen Pernille M, Gordts Philip L S M, Roebroek Anton J M, Frikke-Schmidt Ruth, Tybjaerg-Hansen Anne, Dahlbäck Björn, Nielsen Lars B
Abstract excerpt
ApoM is mainly associated with HDL. Nevertheless, we have consistently observed positive correlations of apoM with plasma LDL cholesterol in humans. Moreover, LDL receptor deficiency is associated with increased plasma apoM in mice. Here, we tested the idea that plasma apoM concentrations are affected by the rate of LDL receptor-mediated clearance of apoB-containing particles. We measured apoM in humans each...
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