Article
Higher dN/dS ratios in the HCV core gene, but not in the E1/HVR1 gene, are associated with human immunodeficiency virus-associated immunosuppression.
Archives of virology - 1 Nov 2012
Xu Chun-Hui, Shen Tao, Zheng Jia-Jia, Tu Jing, Zhang Wei-Dong, Lu Feng-Min
Abstract excerpt
Coinfection with HCV and HIV is prevalent among former commercial blood donors in some rural areas in China. Genetic variability of the HCV core and E1/HVR1 was investigated in 23 patients chronically infected with HCV-1b, with or without concomitant HIV infection. Genetic variability in the core sequence was higher under HIV-associated immunocompromised conditions. Both the Shannon entropy values at each...
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