Article
[Sequence diversity of genotype II/1b hepatitis C virus (HCV) HVR1 of 46 patients in Beijing areas].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Jun 1999
Zhao J, Cheng Y, Zhang H
Abstract excerpt
OBJECTIVE: To study the sequence diversity of the hypervariable region 1(HVR1) in the putative envelope protein E2/NS1 of HCV in Beijing and its neighbouring regions. METHODS: The cDNAs (nt1119-1258) derived from plasma of 46 patients infected with genotype II/1b HCV were amplified, purified and directly sequenced by using RT-nested polymerase chain reaction(PCR) and dideoxynucleotide chain termination method....
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