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Article

Determination of the consequences of VHL mutations on VHL transcripts in renal cell carcinoma.

International journal of oncology - 1 Oct 2012

Taylor Claire, Craven Rachel A, Harnden Patricia, Selby Peter J, Banks Rosamonde E

Abstract excerpt

Genetic and epigenetic changes in the von Hippel-Lindau (VHL) tumour suppressor gene are common in sporadic conventional (clear cell) renal cell carcinoma (ccRCC). The effects on VHL expression are unknown but increased understanding may be relevant clinically, either in terms of prognosis or in therapy selection. We have examined the expression of VHL mutant RNA in 84 ccRCC tumours previously screened for...

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Share to Carcinoma, Renal Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22825683
DOI: 10.3892/ijo.2012.1561
PMCID: PMC3583750

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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