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Investigating the effects of dietary folic acid on sperm count, DNA damage and mutation in Balb/c mice.

Mutation research - 1 Sept 2012

Swayne Breanne G, Kawata Alice, Behan Nathalie A, Williams Andrew, Wade Mike G, Macfarlane Amanda J, Yauk Carole L

Abstract excerpt

To date, fewer than 50 mutagens have been studied for their ability to cause heritable mutations. The majority of those studied are classical mutagens like radiation and anti-cancer drugs. Very little is known about the dietary variables influencing germline mutation rates. Folate is essential for DNA synthesis and methylation and can impact chromatin structure. We therefore determined the effects of folic...

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Identifiers

PMID: 22824165
DOI: 10.1016/j.mrfmmm.2012.07.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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