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Article

Increased type 3 deiodinase expression in papillary thyroid carcinoma.

Thyroid : official journal of the American Thyroid Association - 1 Sept 2012

Romitti Mírian, Wajner Simone Magagnin, Zennig Nadja, Goemann Iuri Martin, Bueno Ana Laura, Meyer Erika L Souza, Maia Ana Luiza

Abstract excerpt

BACKGROUND: Thyroid hormone regulates a wide range of cellular activities, including the balance between cell proliferation and differentiation. The thyroid-hormone-inactivating type 3 deiodinase (DIO3, D3) has been shown to be reactivated in human neoplasias. Here, we evaluated DIO3 expression in human papillary thyroid carcinoma (PTC). METHODS: Tumor and surrounding normal thyroid tissue were collected from 26...

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Source

Identifiers

PMID: 22823995
DOI: 10.1089/thy.2012.0031

Genes

DIO3
BRAF
DIO2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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