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Article

Vitamin D-neutralizing CYP24A1 expression, oncogenic mutation states and histological findings of human papillary thyroid cancer.

Journal of endocrinological investigation - 1 Mar 2015

Balla B, Tobiás B, Kósa J P, Podani J, Horváth P, Nagy Z, Horányi J, Járay B, Székely E, Krenács L, Árvai K, Dank M, Putz Z, Szabó B, Szili B, Valkusz Z, Vasas B, Győri G, Lakatos P, Takács I

Abstract excerpt

OBJECTIVE: The aims of the present study were to examine gene and protein expression of the vitamin D-inactivating 24-hyroxylase (CYP24A1) and the activating 1-alpha-hydroxylase (CYP27B1) enzyme in human papillary thyroid cancer (PTC), furthermore, to investigate the association between CYP24A1 expression and numerous clinical, histological parameters and somatic oncogene mutation status of thyroid tumor tissues....

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Share to 25-Hydroxyvitamin D3 1-alpha-Hydroxylase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Papillary

Share to Gene Expression Regulation, Neoplastic

Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 25201000
DOI: 10.1007/s40618-014-0165-7

Genes

BRAF
HRAS
KRAS
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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