Article
SAP30L (Sin3A-associated protein 30-like) is involved in regulation of cardiac development and hematopoiesis in zebrafish embryos.
Journal of cellular biochemistry - 1 Dec 2012
Teittinen Kaisa J, Grönroos Toni, Parikka Mataleena, Junttila Sini, Uusimäki Annemari, Laiho Asta, Korkeamäki Hanna, Kurppa Kalle, Turpeinen Hannu, Pesu Marko, Gyenesei Attila, Rämet Mika, Lohi Olli
Abstract excerpt
The Sin3A-associated proteins SAP30 and SAP30L share 70% sequence identity and are part of the multiprotein Sin3A corepressor complex. They participate in gene repression events by linking members of the complex and stabilizing interactions among the protein members as well as between proteins and DNA. While most organisms have both SAP30 and SAP30L, the zebrafish is exceptional because it only has SAP30L. Here...
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