Article
Nprl3 is required for normal development of the cardiovascular system.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Aug 2012
Kowalczyk Monika S, Hughes Jim R, Babbs Christian, Sanchez-Pulido Luis, Szumska Dorota, Sharpe Jacqueline A, Sloane-Stanley Jacqueline A, Morriss-Kay Gillian M, Smoot Leslie B, Roberts Amy E, Watkins Hugh, Bhattacharya Shoumo, Gibbons Richard J, Ponting Chris P, Wood William G, Higgs Douglas R
Abstract excerpt
C16orf35 is a conserved and widely expressed gene lying adjacent to the human α-globin cluster in all vertebrate species. In-depth sequence analysis shows that C16orf35 (now called NPRL3) is an orthologue of the yeast gene Npr3 (nitrogen permease regulator 3) and, furthermore, is a paralogue of i...
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