Article
The epidermal growth factor receptor as a therapeutic target in epithelial ovarian cancer.
Cancer epidemiology - 1 Oct 2012
Gui Ting, Shen Keng
Abstract excerpt
A majority of patients with ovarian carcinoma who receive conventional treatment of surgical staging and platinum-based chemotherapy recur and ultimately succumb to their diseases. Novel therapies that target specific pathways involved in ovarian tumorigenesis are rapidly emerging. The epidermal growth factor receptor (EGFR) is overexpressed in 30-98% of epithelial ovarian carcinoma (EOC), and the signaling...
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