Article
EGFR-targeted therapy.
Experimental cell research - 15 Nov 2011
Vecchione Loredana, Jacobs Bart, Normanno Nicola, Ciardiello Fortunato, Tejpar Sabine
Abstract excerpt
Anti-Epidermal Growth Factor Receptor (EGFR) therapies have been recently developed for the treatment of multiple cancer types. At the time when they were introduced in clinical practice, there was little knowledge of the molecular bases of tumor sensitivity and resistance to these novel targeted compounds. By using the framework of anti-EGFR inhibitors as treatment for colorectal cancer patients, we will review...
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