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Article

Recent advances in drug design of epidermal growth factor receptor inhibitors.

Current medicinal chemistry - 1 Jan 2013

Warnault P, Yasri A, Coisy-Quivy M, Chevé G, Boriès C, Fauvel B, Benhida R

Abstract excerpt

The tyrosine kinase epidermal growth factor receptor (EGFR) has emerged in recent years as a key and validated target of targeted therapies for solid tumors. It plays a central role in oncology since it is involved in many steps of tumor progression such as proliferation, angiogenesis, invasiveness, decreased apoptosis, and loss of differentiation. Recent advances in targeted therapies have demonstrated that...

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Source

Identifiers

PMID: 23410174
DOI: 10.2174/0929867311320160001

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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