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Article

A lateral flow biosensor for detection of single nucleotide polymorphism by circular strand displacement reaction.

Chemical communications (Cambridge, England) - 4 Sept 2012

Xiao Zhuo, Lie Puchang, Fang Zhiyuan, Yu Luxin, Chen Junhua, Liu Jie, Ge Chenchen, Zhou Xuemeng, Zeng Lingwen

Abstract excerpt

A lateral flow biosensor for detection of single nucleotide polymorphism based on circular strand displacement reaction (CSDPR) has been developed. Taking advantage of high fidelity of T4 DNA ligase, signal amplification by CSDPR, and the optical properties of gold nanoparticles, this assay has reached a detection limit of 0.01 fM.

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PMID: 22810628
DOI: 10.1039/c2cc33931e

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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