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Article

Homeostatic adaptations in brain energy metabolism in mouse models of Huntington disease.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 1 Nov 2012

Tkac Ivan, Henry Pierre-Gilles, Zacharoff Lori, Wedel Michael, Gong Wuming, Deelchand Dinesh K, Li Tongbin, Dubinsky Janet M

Abstract excerpt

Impairment of energy metabolism is a key feature of Huntington disease (HD). Recently, we reported longitudinal neurochemical changes in R6/2 mice measured by in-vivo proton magnetic resonance spectroscopy ((1)H MRS; Zacharoff et al, 2012). Here, we present similar (1)H MRS measurements at an ear...

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Identifiers

PMID: 22805874
DOI: 10.1038/jcbfm.2012.104
PMCID: PMC3493992

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22805874-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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