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Article

A distinct de novo expression of Nav1.5 sodium channels in human atrial fibroblasts differentiated into myofibroblasts.

The Journal of physiology - 1 Sept 2012

Chatelier Aurélien, Mercier Aurélie, Tremblier Boris, Thériault Olivier, Moubarak Majed, Benamer Najate, Corbi Pierre, Bois Patrick, Chahine Mohamed, Faivre Jean François

Abstract excerpt

Fibroblasts play a major role in heart physiology. They are at the origin of the extracellular matrix renewal and production of various paracrine and autocrine factors. In pathological conditions, fibroblasts proliferate, migrate and differentiate into myofibroblasts leading to cardiac fibrosis. This differentiated status is associated with changes in expression profile leading to neo-expression of proteins such...

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Identifiers

PMID: 22802584
DOI: 10.1113/jphysiol.2012.233593
PMCID: PMC3473287

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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