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Article

Electrical remodeling in atrial fibrillation.

Herz - 1 Apr 2006

Dobrev Dobromir

Abstract excerpt

Electrical remodeling refers to any change in electrical function that promotes atrial fibrillation (AF). A key advance in understanding the mechanisms of AF has been the identification of ion channels, gap junctions and regulators of intracellular Ca(2+) homeostasis as the molecular determinants of abnormal atrial electrical activity, and how these are modified in AF. This review focuses on the cellular and...

Topics

Action Potentials
Angiotensin-Converting Enzyme Inhibitors
Animals
Anti-Arrhythmia Agents
Atrial Fibrillation
Atrial Function
Calcium
Disease Models, Animal
Dogs
Gap Junctions
Heart Atria
Heart Rate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Homeostasis

Humans

Ion Channels

Mutation

Signal Transduction

Source

Identifiers

PMID: 16738832
DOI: 10.1007/s00059-006-2787-9

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