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Article

Estimation of the difference in HbF expression due to loss of the 5' δ-globin BCL11A binding region.

Haematologica - 1 Feb 2013

Ghedira Elyes Slim, Lecerf Laure, Faubert Emmanuelle, Costes Bruno, Moradkhani Kamran, Bachir Dora, Galactéros Frédéric, Pissard Serge

Abstract excerpt

BCL11A was the focus of recent studies on its inhibiting effect when bound onto the β-globin cluster in the mechanism of hemoglobin switching and HbF downregulation. We examined a cohort of 10 patients displaying different HbF levels and short deletions within the γβ-δ intergenic region to find a...

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Identifiers

PMID: 22801970
DOI: 10.3324/haematol.2012.061994
PMCID: PMC3561440

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22801970-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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