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Defective apoptotic cell clearance activates innate immune response to protect Caenorhabditis elegans against pathogenic bacteria.

Virulence - 1 Dec 2021

Wan Jinlong, Yuan Lei, Jing Huiru, Zheng Qian, Xiao Hui

Abstract excerpt

Appropriate clearance of dead cells generated by apoptosis is critical to the development of multicellular organisms and tissue homeostasis. In mammals, the removal of apoptotic cell is mediated by polarized monocyte/macrophage populations of the innate immune system. The innate immune system is essential for anti-viral and anti-microbial defense. However, our current understanding of the relationship between...

Topics

Animals
Apoptosis
Bacteria
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Immunity, Innate
MAP Kinase Signaling System
Mitogen-Activated Protein Kinases
Mutation
Phagocytosis
Pseudomonas aeruginosa

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Salmonella typhimurium

p38 Mitogen-Activated Protein Kinases

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Open in PubMed Open full text

Identifiers

PMID: 33372828
DOI: 10.1080/21505594.2020.1857982
PMCID: PMC7781629

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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